Cannabis has historically been stigmatized due to its effects, but it is now gaining recognition for its potential in various medical fields. Recent years have seen a significant increase in research into the therapeutic properties of cannabis, especially its advantages for neurological conditions.
Beyond its well-known applications for stress relief, alleviating depression, and enhancing sleep, cannabis shows promise in addressing a wide range of neurological disorders. In this article, we explore five such conditions and investigate how a Pacific Green Canada product or cannabis plays a role in their therapeutic applications.
Table of Contents
Key Takeaways:
- Certain cannabinoids and terpenes demonstrate unique effects on various neurological disorders.
- Linalool, myrcene, and limonene possess anti-convulsant properties.
- Equal concentrations of THC and CBD, along with other cannabis compounds, show potential in cancer treatment.
A Natural Approach to Managing Neurological Disorders
The approach to addressing the complexities of conditions such as Alzheimer’s disease (AD), brain tumors, Parkinson’s disease (PD), intractable epilepsy, and chronic traumatic encephalopathy (CTE) varies based on individual patient needs and disease extent.
Cannabis is a Viable Treatment Option
Epilepsy
The endocannabinoid system influences the seizure threshold. THC, in particular, can significantly reduce seizures, unlike other treatments. Studies have shown spikes in endocannabinoid production and sustained increases in CB1 production over time. Researchers have noted the anti-convulsant properties of cannabinoids, even at non-sedating levels.
THC, THCA, and linalool, a terpenoid found in cannabis, have been subjects of scientific exploration. The conversation around THCA is intricate, focusing on its CB1 activity and its conversion to THC.
Recent research highlights the anti-convulsant properties of cannabidiolic acid (CBDA), suggesting its serotonergic effects. CBDA shows a significantly higher affinity for the 5-HT1A receptor than CBD.
If you are interested in exploring cannabis vape pens to assist with your condition, look for products containing THC, CBD, THCA, or Linalool.
The Pacific Green Canada – THC Distillate Disposable Vape pen Skittlez contains linalool as one of its primary terpenes, with THC levels ranging from 16 to 21%.
Brain Tumors
Numerous studies have examined the use of cannabis in patients diagnosed with brain tumors. Research published in the British Journal of Cancer found that administering THC directly into tumors in patients with glioblastoma multiforme (GBM) slightly extended their life expectancy in nine cases.
Additionally, a case report detailed the complete regression of residual tumors in two children with pilocytic astrocytomas after cannabis use.
THCA, as a peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, demonstrates greater potential impact than CBDA, CBD, or THC. PPARs serve as ligand-binding transcription factors, targeting cancer cells selectively while sparing normal cells. The synergistic effects of THCA with other cytotoxic agents underscore its potential in cancer therapy.
Equal concentrations of THC and CBD, combined with THCA, CBDA, and cytotoxic terpenoids like limonene, hold considerable promise in cancer treatment, as suggested by a study in the Planta Medicine Journal. Disposable cannabis pens can encapsulate these cannabinoids and terpenes in one cartridge.
Parkinson’s Disease
An observational study indicated that 22 out of 28 patients could tolerate smoked cannabis, presumed to be THC-predominant. The study highlighted acute benefits, including improvements in tremor, rigidity, and bradykinesia.
In Parkinson’s disease, the loss of cells in the substantia nigra leads to widespread pathology over time. Changes in tau proteins contribute to neurofibrillary tangles.
Nabiximols, a cannabis-based oral spray, significantly reduced tangles when administered to mice expressing human tau. This treatment improved dopamine metabolism and glial function while reducing oxidative stress levels.
THC vape pens like Pacific Green Canada can be an excellent option if you wish to manage tremors.
Alzheimer’s Disease
Alzheimer’s disease (AD) involves the formation of senile plaques from β-amyloid (Aβ) proteins and the buildup of neurofibrillary tangles from tau proteins. Once these processes commence, disease progression is inevitable.
CBD acts as a protective antioxidant for the brain, interacting safely with NMDA receptors. It combats Alzheimer’s disease by inhibiting Aβ plaque formation, reducing harmful ROS production, and preventing damage to fats in affected cells. CBD also prevents tau proteins from acquiring excessive phosphate groups.
In a study, patients received THC-predominant, CBD-predominant, and THCA, primarily through tinctures and confections. Participants reported reduced dependency on neuroleptic drugs, less agitation, improved appetite, better sleep quality, and pain management.
The components of cannabis show potential in addressing various symptoms associated with this complex disorder:
- Agitation may be relieved by THC, CBD, and linalool.
- Psychosis symptoms may benefit from CBD.
- THC and linalool may alleviate insomnia and restlessness.
- THC is indicated for anorexia, while THC, CBD, and linalool may assist with aggression.
- THC, limonene, and CBD could help manage depression.
- THC and CBD offer pain-relieving properties.
- Alpha-pinene, along with THC, aids in memory enhancement.
- CBD and THC are associated with neuroprotection, while THC, CBD, and THCA may contribute to reduced Aβ plaque formation.
Traumatic Brain Injury / Chronic Traumatic Encephalopathy
Cannabis, especially chemovars combining THC and CBD, can ease symptoms associated with CTE, such as headaches, nausea, insomnia, dizziness, agitation, substance abuse, and psychosis.
A 2019 study revealed that varying THC and CBD concentrations help alleviate stress, agitation, depression, and anxiety in chronic traumatic encephalopathy cases. Cannabinoids reduce glutamate excitotoxicity, preventing nerve cell damage post-injury.
Want to Use cannabis for Your Current Condition?
Utilizing cannabis is a common method to leverage its benefits. If you’re looking to avoid potential health risks associated with traditional methods, cannabis vapes present a viable alternative.
Weed vape pens feature a heating chamber that transforms the flower or concentrate into vapor. Online cannabis stores provide numerous options to help you find the ideal vape pen for your needs, allowing you to select based on pen type, including disposable vape pens, Sativa-dominant or Indica-dominant cartridges with high THC, or specific concentrates.
Weed Vape Pens Treat Your Condition
Neurological treatment for the conditions discussed requires significant advancements. However, emerging methods like cannabis use, including through a cannabis, in treatment protocols show promise. Research studies and anecdotal evidence suggest that cannabis, with varying levels of THC, CBD, and other compounds, can interact with the ECS to help manage symptoms of these conditions.
Frequently Asked Questions
Can a dab pen provide the same experience as a vape pen?
A dab pen and a vape pen both vaporize cannabis concentrates but differ in intensity and application. Dab pens are designed for solid concentrates like wax, producing a more intense effect, while vape pens use liquid concentrates, offering a milder, more controlled experience.
Are THC pens cheap?
The average cost of a cannabis pen is around $50, with options ranging from $20 to over $200, depending on battery life and features.
Can my current medication interact with the active ingredient in my cannabis vape?
This depends on your prescription. If you take anti-depressants while managing Parkinson’s disease, cannabis may initially increase serotonin, which could exacerbate depression and anxiety over time. It’s best to consult your doctor before adding cannabis to your medication regimen.
Are cannabis pens the best alternative when treating health issues with cannabis?
Weed pens provide a cleaner method to use cannabis without the smoke from combustion, making them popular for those seeking less harmful and more discreet options for health issues like pain and anxiety.
However, whether cannabis pens are the best choice can depend on the individual. Since we are still learning about their long-term effects, it is crucial for anyone considering them for health reasons to consult a doctor first, ensuring they select the best method for their health needs.
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